Magnetic Mixers

Aseptic Magnetic Coupled Mixers

High torque bottom-mounted magnetic mixers for volumes to 50,000 liters

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The obvious advantage of the Zeta bottom-mounted magnetic mixers is the containment shell hermetically seals off the internal space of the vessel from the surrounding atmospheric environment maintaining the integrity of the mixing vessel.  Mechanical seals are not required.  The respective risks and disadvantages of mechanical seals (i.e., leakage, germination, maintenance effort) are eliminated.

Specific focus is placed on the cleanability of our magnetic agitators – a necessity for sterile application.  A key design feature is the large gap between the containment shell and the magnet ring.  This reduces any shear forces in this area and helps greatly with cleaning.  QHD trained employees and independent testing according to EHEDG guidelines guarantee that these agitators can be validated in the most demanding processes.  Various models of bottom-mounted or top-mounted magnetic agitators are available.

The design of the standard magnetically coupled mixer impeller, which is suitable for most applications, offers important advantages for our BMR magnetic agitators:
Open, easy to clean design assures total cleanability in place by spray ball alone, as the hub and magnetic rotor are connected only by the impeller blades
Very large circular gap between containment shell and rotor offers maximum flow rate and low shear stress.

Careful attention to universally accepted CIP/SIP design standards, includes using beveled surfaces with no sharp angles and a high level of surface finish eliminates the potential
for product residue by getting rid of dead legs, hidden areas, and cavities that are the source of down stream contamination.

Ceramic slide bearing (Silicon-Carbide vs. Zirconium-Oxide) oversized in terms of diameter and height, for high stability, exceptional sliding properties in low volume situations, and
particle generation below detectable levels.

Ease of maintenance – replacing of the female ceramic bushing can be done by the user on site CFD investigated mixing results: Radially pumping, with liquid draw from the top. For effective blending, good heat transfer. Suitable for drawing in powdered solids.

Sizing to your process requirements (i.e., low shear stress or vigorous mixing).

Mixing to minimal volumes:  A special advantage of our magnetic impeller is the “floating bearing system”: The kinked shape of the impeller wings generates a floating action of the mixing head due to hydraulic effects. An oscillating movement is generated on the product lubricated pivot of the slide bearing. Advantage: reduced load for the axial bearing and better flow rate in the bearing gap which result in a superior lubricating effect and improved cleaning properties.

 

 

Proven Technology - Open Design - Widest Range
Type
Ø Impeller mm
Rated Power kW
Max Speed rpm
Annular Gap Containment Shell mm
Mixing Capacity (depending on task) liter
BMR 30 M
80
0.09
900
640 MF
5 to 120
BMR 75
105
0.18
850
2.0
50 to 250
BMR 75 M
105
0.12
850
3.3
50 to 250
BMR 100
125
0.18
525
3.3
100 to 400
BMR 300
150
0.25
575
3.3
200 to 800
BMR 550
175
0.37
530
3.5
500 to 1700
BMR 550 M
110
0.75
1150
4.5
800 to 3000
BMR 850
210
0.55
440
4.5
800 to 3000
BMR 1200
250
0.75
325
7.0
1000 to 4000
BMR 2500
300
1.10
300
7.0
2000 to 8000
BMR 2500 M
165
2.20
900
7.0
3000 to 10000
BMR 4000
350
1.50
250
7.0
3500 to 12000
BMR 7500
400
2.20
250
7.0
6000 to 22000
BMR 13000
450
4.00
240
7.0
10000 to 33000
BMR 20000
200
7.50
230
7.0
15000 to 45000

Advantages of Zeta Bio-M mixers

The zeta product range of mixing and agitating systems combines many years of experience in process engineering,
exceptional aseptic design, and manufacturing know-how.
bio-m® Agitators for all applications in sterile process engineering

zeta agitators are being used in validated processes, by the leading pharmaceutical and biotechnology manufacturing companies where the highest requirements are set for sterile design and reliability:
– Bio reactors for bacteria and cell cultures
– Processes with carrier-suspensions
– Production of vaccines
– Process vessels in the upstream and downstream areas
of fermentation plants including Bio kill tanks
– Infusion and injection solutions
– Blood plasma fractionation
– Active Pharmaceutical Ingredients (API)
– Fine chemistry
– Food and Beverage Industries
– Breweries
– Dairy industry
– Fruit juice production including pulp suspension
– Special applications
– High pressure reactors
– Cooling media

Expert Support

PharmAseptic has 20 years experience with magnetic coupled mixer systems in a wide range of pharmaceutical, biotech, dairy and beverage applications.

For critical applications we offer development capabilities as well computer fluid dynamics (CFD) studies.

Mixing Tasks

The first task for is to collect the relevant process data. Based upon this information, we then complete the process engineering function of sizing agitators for the mixing task to be performed.
All agitator components are determined from this data (i.e., type of impeller and diameter, speed, motor capacity, etc.).

The following typical mixing tasks may be required individually or in combined form:
Blending
Mixing of liquids of similar type
Criteria for sizing: desired mixing time and mixing quality
Suspending
Keeping solids spread in a liquid
(Important for dissolving solids = mass transfer solid -> liquid)
Criteria for sizing: required degree of suspension
Required information: size, density, and quantity of particles
Heat Transfer
To improve heat transfer in cooled, as well as in heated vessels
Criteria for sizing: required internal heat transfer αi (calorimetric product data has to be stated and
upon request, zeta also calculates the complete heat transfer of a vessel)
Gassing
Dispersing of introduced gas quantities for improving the mass transfer
Criteria for sizing: reliable and favorable distribution of the introduced gas quantity
without agitator overflow, resulting in optimal mass transfer
(the gas quantity has to be stated)
Dispersing
Dispersing of liquids which cannot be mixed (i.e., Oil – water)
Criteria for sizing: optimising of mass transfer
zeta owns computation programs and other materials that permit optimal sizing and configuration so that
each agitator is adapted to the mixing task.

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