Top Mounted – Magnetic Coupling – External Bearing
For applications which require a magnetic agitator mounted on the cover of the vessel, PharmAseptic offers the Liquitec TMAe series top-mounted magnetic agitators. The key difference from the TMAi agitator is the location of the bearings outside the vessel. These agitators avoid the problems of conventional systems with mechanical seals and permit the use of almost any type of impeller. The impellers can be welded to the shaft or mounted with the aid of a sliding hub in sterile design. Liquitec TMAe with internal magnetic coupling, for vessel volumes between 2 and 150 liters. On these agitators with torques between 0.3 und 5.5 Nm, the magnetic coupling and the dry running shaft bearings project into the product space and can thus – in contrast to normal laboratory agitators – be cleaned in-situ together with the inside of the vessel. The mounting on the vessel cover with, for example, a dead-leg-free flange, a TriClamp or a bayonet connector is executed in accordance with the customer‘s wishes. Process-specific impellers, such as a segment impeller („Elephant ear“) for cell culture fermentation, Rushton turbines or pitched blade impellers, are mounted on the shaft. AC motors suitable for Variable Frequency Control (VFD) operation are standard, and as an option, can be supplied with integrated frequency converters. For small sizes, DC motors with integrated speed control are supplied. Quick-change couplings for the drive are available as an option.
Liquitec TMAe Magnetic Agitators are designed in accordance with state of the art technology to ensure that they can be both cleaned and sterilized. Agitators are both designed for CIP (Cleaning in Place) and SIP (Sterilization in Place). The cleaning or sterilization time depends on the process and must be determined by the user.
Advantages for aseptic processing
• Magnetic coupling eliminates mechanical seal
• No elaborate supply systems requiring qualification, thus low operating and validation costs
• Can be mounted onto an existing vessel flange if, e.g., an existing mechanical seal mixer is to be replaced
• All impeller types are possible